Reducing cardiovascular disease risk in patients with type 2 diabetes and concomitant macrovascular disease: can insulin be too much of a good thing?

@article{Rensing2011ReducingCD,
  title={Reducing cardiovascular disease risk in patients with type 2 diabetes and concomitant macrovascular disease: can insulin be too much of a good thing?},
  author={Katrijn L. Rensing and Anne Q. Reuwer and Benoit J. Arsenault and Jan H. von der Th{\"u}sen and Joost B. L. Hoekstra and John J. P. Kastelein and Th B Marcel Twickler},
  journal={Diabetes, obesity & metabolism},
  year={2011},
  volume={13 12},
  pages={1073-87}
}
Despite improvement of microvascular outcomes as a consequence of optimal glucose control in patients with type 2 diabetes, prevention of macrovascular complications is still a major challenge. Of interest, large-scale intervention studies (Action to Control Cardiovascular Risk in Diabetes, Action in Diabetes and Vascular Disease-Preterax and Diamicron Modified Release Controlled Evaluation and Veterans Affairs Diabetes Trial) comparing standard therapy versus more intensive glucose-lowering… CONTINUE READING

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