Reducing antimicrobial use in food animals

@article{VanBoeckel2017ReducingAU,
  title={Reducing antimicrobial use in food animals},
  author={Thomas P. Van Boeckel and Emma E. Glennon and Dora DongZhi Chen and Marius Gilbert and Timothy P. Robinson and Bryan T. Grenfell and Simon Asher Levin and Sebastian Bonhoeffer and Ramanan Laxminarayan},
  journal={Science (New York, N.y.)},
  year={2017},
  volume={351},
  pages={1350 - 1352}
}
Consider user fees and regulatory caps on veterinary use The large and expanding use of antimicrobials in livestock, a consequence of growing global demand for animal protein, is of considerable concern in light of the threat of antimicrobial resistance (AMR). Use of antimicrobials in animals has been linked to drug-resistant infections in animals (1) and humans (2). In September 2016, the United Nations (UN) General Assembly recognized the inappropriate use of antimicrobials in animals as a… 

Global Trends in Antimicrobial Use in Food Animals from 2017 to 2030

The results show lower global antimicrobial sales in 2030 compared to previous estimates, owing to recent reports of decrease in antimicrobial use, in particular in China, the world’s largest consumer.

Antimicrobial resistance at the livestock-human interface: implications for Veterinary Services.

Robust AMU and AMR data are important to monitor the progress of interventions aiming to reduce AMR in the livestock sector, but not all countries have complete data on antibiotic sales or use, so current knowledge of global AMU is primarily based on modelling estimates.

Review on Antimicrobial Usage in Food Animals: Challenges in Ethiopia and its Future Perspectives

DOI: 10.21276/sjavs.2018.5.9.1 Abstract: Antimicrobials are used in livestock production to maintain health and productivity. Antimicrobial agents are used throughout the world, across a diverse

Antimicrobial use in food animals and human health: time to implement ‘One Health’ approach

Concerted and collaborative efforts among all the stakeholders are essential to deal with this complex problem of resistance.

Excessive use of medically important antimicrobials in food animals in Pakistan: a five-year surveillance survey

The findings suggest that the annual consumption of antimicrobials in the broiler sector in Pakistan could be as high as 568 tons, which is an alarmingly high consumption estimate.

Global trends in antimicrobial use in aquaculture

This analysis calls for a substantial scale-up of surveillance capacities to monitor global trends in antimicrobial use and highlights the urgent need for enhanced antimicrobial stewardship in a high-growth industry with broad links to water and ecosystem health.

Global trends in antimicrobial resistance in animals in low- and middle-income countries

The current study provides a much-needed baseline model for low- and middle-income countries and provides a “one health” perspective to which future data can be added, and produces global maps of AMR in LMICs to give policy-makers—or a future international panel—a baseline for monitoring AMR levels in animals and target interventions in the regions most affected by the rise of resistance.

Quantifying the Relationship between Antibiotic Use in Food-Producing Animals and Antibiotic Resistance in Humans

This work outlines and compares methods that can be used to estimate the relationship between food-producing animal antimicrobial use and AMR in humans, and provides recommendations for future panel regression studies to follow to inform cost-effectiveness analyses of AMR containment interventions across the One Health spectrum.
...

References

SHOWING 1-10 OF 21 REFERENCES

Global trends in antimicrobial use in food animals

The first global map (228 countries) of antibiotic consumption in livestock is presented and it is projected that antimicrobial consumption will rise by 67% by 2030, and nearly double in Brazil, Russia, India, China, and South Africa.

The Economic Costs of Withdrawing Antimicrobial Growth Promoters from the Livestock Sector

The growth response to AGPs appears to be small in optimised production systems, suggesting that the economic impacts of a ban on AGPs could be limited in high-income industrialized countries but potentially higher in lower income countries with less developed hygiene and production practices.

The livestock reservoir for antimicrobial resistance: a personal view on changing patterns of risks, effects of interventions and the way forward

  • F. Aarestrup
  • Biology, Medicine
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2015
There is a need for global harmonized integrated and continuous surveillance of antimicrobial usage and antimicrobial resistance, preferably associated with data on production and animal diseases to determine the positive and negative impact of reducing antimicrobial use in livestock.

Modelling the impact of curtailing antibiotic usage in food animals on antibiotic resistance in humans

It is suggested that, for a wide range of scenarios, curtailing the volume of antibiotics consumed by food animals has little impact on the level of resistance in humans and that reducing the rate of transmission of resistance from animals to humans may be more effective than an equivalent reduction in the consumption of antibiotics in food animals.

Antimicrobial Usage in Chicken Production in the Mekong Delta of Vietnam

Antimicrobials are used extensively in chicken production in Vietnam, but to date no quantitative data are available. A 2012–2013 survey of 208 chicken farms in Tien Giang province, stratified by

Learning from agriculture: understanding low-dose antimicrobials as drivers of resistome expansion

This review focuses on agricultural antimicrobial use as a laboratory for understanding low-dose antimicrobials as drivers of resistome expansion, briefly summarizes current knowledge, highlights the importance of research specifically on environmental microbial ecosystems considering AMR as environmental pollution, and calls attention to the needs for longitudinal studies at the systems level.

Raised Without Antibiotics: Lessons from Voluntary Labeling of Antibiotic Use Practices in the Broiler Industry

Voluntary labeling improves market efficiency if consumers receive the product characteristics they demand and producers are compensated for producing these characteristics. For this to occur, label

Antibiotic effectiveness: Balancing conservation against innovation

This paper assesses the relative benefits and costs of conservation and innovation in making the best use of current antibiotic effectiveness.

Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates.

Susceptibility data suggest that erythromycin and other macrolides should remain the drugs of choice in most regions, with systematic surveillance and control measures maintained, but fluoroquinolones may now be of limited use in the empiric treatment of Campylobacter infections in many regions.

Associations between the use of antimicrobial agents for growth promotion and the occurrence of resistance among Enterococcus faecium from broilers and pigs in Denmark, Finland, and Norway.

The use of antimicrobial agents for growth promotion in Denmark, Finland, and Norway have selected for resistance to most of these drugs among E. faecium in food animals.