Reduced thickness of medial orbitofrontal cortex in smokers.

  title={Reduced thickness of medial orbitofrontal cortex in smokers.},
  author={Simone K{\"u}hn and Florian Schubert and J{\"u}rgen Gallinat},
  journal={Biological psychiatry},
  volume={68 11},
BACKGROUND Structural deficiencies within the prefrontal cortex might be related to drug-taking behavior that prevails in smokers. Cortical thickness has been found to be a structural modulator of cerebral function and cognition and a subtle correlate of mental disorders. However, to date an analysis of cortical thickness in smokers compared with never-smokers has not been undertaken. METHODS We acquired high-resolution magnetic resonance imaging scans from 22 smokers and 21 never-smokers and… CONTINUE READING
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