Reduced temporal lobe blood flow in Alzheimer's disease.

  title={Reduced temporal lobe blood flow in Alzheimer's disease.},
  author={J. L. Eberling and William J. Jagust and Bruce R. Reed and Mary Gray Baker},
  journal={Neurobiology of aging},
  volume={13 4},
We used single photon emission computed tomography with the blood flow tracer [123I]N-isopropyl-p-iodoamphetamine (IMP) to study regional cerebral blood flow (rCBF) in 50 mildly and moderately demented Alzheimer's disease (AD) patients to evaluate rCBF as a function of disease severity. Relative rCBF (normalized to occipital cortex) was significantly lower… CONTINUE READING