Reduced susceptibility to ciprofloxacin and gyra gene mutation in North Indian strains of Salmonella enterica serotype Typhi and serotype Paratyphi A.

@article{Renuka2004ReducedST,
  title={Reduced susceptibility to ciprofloxacin and gyra gene mutation in North Indian strains of Salmonella enterica serotype Typhi and serotype Paratyphi A.},
  author={Kalyani Renuka and Arti Kapil and Susheel Kumar Kabra and Naveet Wig and Bimal Kumar Das and V V S P Prasad and Rama Chaudhry and Pradeep Seth},
  journal={Microbial drug resistance},
  year={2004},
  volume={10 2},
  pages={146-53}
}
The emergence of reduced susceptibility to ciprofloxacin among Salmonella enterica serotype Typhi and serotype Paratyphi A leading to clinical failure of treatment poses a great therapeutic challenge. The mechanism of fluoroquinolone resistance in clinical isolates of S. Typhi and S. Paratyphi A is not very well documented. The present study was carried out with the objective of molecular characterization of reduced quinolone susceptibility amongst the strains of S. Typhi and S. Paratyphi A… CONTINUE READING

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