Reduced sleep and impaired sleep initiation in adult male rats exposed to alcohol during early postnatal period

@article{Volgin2012ReducedSA,
  title={Reduced sleep and impaired sleep initiation in adult male rats exposed to alcohol during early postnatal period},
  author={Denys V. Volgin and Leszek Kubin},
  journal={Behavioural Brain Research},
  year={2012},
  volume={234},
  pages={38-42}
}
Prenatal alcohol exposure (AE) is associated with cognitive and neurobehavioral abnormalities, such as increased motor activity and elevated anxiety, that may last a lifetime. Persistent sleep disruption may underlie these problems. Using a rat model, we investigated long-term alterations of sleep-wake behavior following AE during a critical early developmental period. Male rats received 2.6 g/kg of alcohol intragastrically twice daily on postnatal days (PD) 4-9, a developmental period… CONTINUE READING

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Adult rats exposed to alcohol during perinatal period have altered REM sleep amounts and sleep initiation

DV Volgin, L Kubin
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Pre - adolescent rats exposed to alcohol during perinatal period have reduced glutamate decarboxylase ( GAD ) levels in sleepand wakeregulating hypothalamic regions

DV Volgin, L Kubin
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