Reduced serum somatomedin activity in patients with chronic liver disease.

@article{Wu1974ReducedSS,
  title={Reduced serum somatomedin activity in patients with chronic liver disease.},
  author={A Wu and David B. Grant and Judy Hambley and Allan J. Levi},
  journal={Clinical science and molecular medicine},
  year={1974},
  volume={47 4},
  pages={359-66}
}
1. Somatomedin (SM; sulphation factor) activity was estimated by a chick-cartilage assay in fasting sera from twenty-one patients with chronic liver disease. 2. Low SM values were found in nine out of the ten patients with cirrhosis and in two other patients, one with hepatofibrosis and one with hepatoma. 3. In general, the lowest serum SM activities were found in those patients with the most severe disease and significant correlations were found between serum SM and serum albumin, alkaline… CONTINUE READING