Reduced risk of NSAID gastropathy (GI mucosal toxicity) with nonacetylated salicylate (salsalate): an endoscopic study.

@article{Roth1990ReducedRO,
  title={Reduced risk of NSAID gastropathy (GI mucosal toxicity) with nonacetylated salicylate (salsalate): an endoscopic study.},
  author={Sanford H. Roth and Ralph Bennett and P H Caldron and Richard A Hartman and Christina A Mitchell and M M Doucette and Birgit Ekholm and Barry Goldlust and E Lee and Robert Michael Wilson},
  journal={Seminars in arthritis and rheumatism},
  year={1990},
  volume={19 4 Suppl 2},
  pages={11-9}
}
This randomized, investigator-blinded, parallel group endoscopic study evaluated the effects of salsalate and naproxen on the gastroduodenal mucosa over a 3-month period in patients with RA. Using therapeutic doses of the drugs, 8 of 21 patients (38%) in the naproxen group had endoscopically shown active ulcers (seven patients) or diffuse erosions (one… CONTINUE READING