Reduced response-inhibition in obsessive-compulsive disorder measured with topographic evoked potential mapping.

@article{Herrmann2003ReducedRI,
  title={Reduced response-inhibition in obsessive-compulsive disorder measured with topographic evoked potential mapping.},
  author={Martin J. Herrmann and Christian Peter Jacob and Stefan Unterecker and Andreas J. Fallgatter},
  journal={Psychiatry research},
  year={2003},
  volume={120 3},
  pages={265-71}
}
Recent neuroimaging studies have suggested that a hyperactivity of the frontal-striate neuronal circuits, including the orbitofrontal cortex and the basal ganglia, mediates the symptomatology of obsessive-compulsive disorder (OCD). However, there is also some evidence that the superior frontal cortex is less activated in OCD, and this local hypoactivity has been shown to be negatively associated with the symptomatology. As the superior frontal cortex is believed to be involved in inhibitory… CONTINUE READING
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