Reduced renal Na+-K+-Cl- co-transporter activity and inhibited NKCC2 mRNA expression by Leptospira shermani: from bed-side to bench.

@article{Wu2004ReducedRN,
  title={Reduced renal Na+-K+-Cl- co-transporter activity and inhibited NKCC2 mRNA expression by Leptospira shermani: from bed-side to bench.},
  author={Mai-Szu Wu and C. -H. Yang and Ming-jen Pan and Chiz-Tzung Chang and Yung-Chih Chen},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2004},
  volume={19 10},
  pages={2472-9}
}
BACKGROUND Renal involvement is common in leptospirosis. Interstitial nephritis with interstitial oedema and mononuclear cellular infiltration are the usual findings. Clinically, non-oligouric acute renal failure, hypokalaemia and sodium wasting appear frequently in leptospirosis. The outer membrane protein from leptospira has been thought to be responsible for the disorder. However, the exact mechanisms of renal involvement are still unclear. METHODS To address these questions, we first… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Renal magnesium wasting and tubular dysfunction in leptospirosis.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2008
View 7 Excerpts
Highly Influenced

Cardiac involvement in leptospirosis.

Transactions of the Royal Society of Tropical Medicine and Hygiene • 2012

References

Publications referenced by this paper.
Showing 1-10 of 19 references

Leptospirosis associated with hypokalaemia and thick ascending limb dysfunction.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 1999
View 1 Excerpt

Physiological significance of volume-regulatory transporters.

American journal of physiology. Cell physiology • 1999
View 1 Excerpt

Leptospirosis: an ignored cause of acute renal failure in Taiwan.

American journal of kidney diseases : the official journal of the National Kidney Foundation • 1997
View 5 Excerpts

Similar Papers

Loading similar papers…