Reduced plasma concentrations of nitrogen oxide in individuals with essential hypertension.

@article{Node1997ReducedPC,
  title={Reduced plasma concentrations of nitrogen oxide in individuals with essential hypertension.},
  author={Koichi Node and Masafumi Kitakaze and Hideto Yoshikawa and Hiroaki Kosaka and Masatsugu Hori},
  journal={Hypertension},
  year={1997},
  volume={30 3 Pt 1},
  pages={405-8}
}
Patients with essential hypertension exhibit blunted endothelium-dependent vasodilator responses, which may be largely attributable to reduced bioactivity of nitric oxide (NO). Therefore, we measured the end product of NO, nitrate plus nitrite (nitrogen oxide), and examined the relationship between the degree of hypertension and plasma nitrate plus nitrite levels in patients with essential hypertension. The combined plasma concentration of nitrate plus nitrite, end products of NO metabolism… CONTINUE READING

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