Reduced phosphodiesters and high-energy phosphates in the frontal lobe of schizophrenic patients: a (31)P chemical shift spectroscopic-imaging study.

@article{Volz2000ReducedPA,
  title={Reduced phosphodiesters and high-energy phosphates in the frontal lobe of schizophrenic patients: a (31)P chemical shift spectroscopic-imaging study.},
  author={Harald Volz and Stefan Riehemann and Iris Maurer and Stefan Smesny and Martin Sommer and Reinhard Rzanny and Werner Holstein and J{\"o}rg Czekalla and Heinrich Sauer},
  journal={Biological psychiatry},
  year={2000},
  volume={47 11},
  pages={954-61}
}
BACKGROUND (31)Phosphorous magnetic resonance spectroscopy has been widely used to evaluate schizophrenic patients in comparison to control subjects, because it allows the investigation of both phospholipid and energy metabolism in vivo; however, the results achieved so far are inconsistent. Chemical shift imaging (CSI) has the advantage that instead of only one or a few preselected voxels the tissue of a whole brain slice can be examined. The aim of the present investigation was to determine… CONTINUE READING

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