Reduced oxygen concentration improves the developmental competence of mouse oocytes following in vitro maturation.

@article{Preis2007ReducedOC,
  title={Reduced oxygen concentration improves the developmental competence of mouse oocytes following in vitro maturation.},
  author={Kimberly A Preis and George E. Seidel and David K Gardner},
  journal={Molecular reproduction and development},
  year={2007},
  volume={74 7},
  pages={893-903}
}
Reduced atmospheric oxygen concentration is beneficial to embryo development; however, optimal oxygen concentration for oocyte maturation remains undetermined. Likewise, there is no consensus of appropriate medium supplementation during maturation. The objective of this study was to determine whether oxygen tension (20% or 5% O2) and epidermal growth factor (EGF) affect oocyte metabolism and subsequent embryo development. Cumulus-oocyte complexes (COCs) were collected from 28-day-old equine… CONTINUE READING

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