Reduced monomeric CD4 is the preferred receptor for HIV.

Abstract

CD4 is a co-receptor for binding of T cells to antigen-presenting cells and the primary receptor for the human immunodeficiency virus type 1 (HIV). CD4 exists in three different forms on the cell surface defined by the state of the domain 2 cysteine residues: an oxidized monomer, a reduced monomer, and a covalent dimer linked through the domain 2 cysteines… (More)
DOI: 10.1074/jbc.M110.190579

Topics

6 Figures and Tables

Cite this paper

@article{Matthias2010ReducedMC, title={Reduced monomeric CD4 is the preferred receptor for HIV.}, author={Lisa J. Matthias and Iman Azimi and Catherine Ann Tabrett and Philip J Hogg}, journal={The Journal of biological chemistry}, year={2010}, volume={285 52}, pages={40793-9} }