Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.

@article{Avila2000ReducedMA,
  title={Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.},
  author={Mat{\'i}as A. Avila and Carmen Berasain and Luis Alberto Berm{\'u}dez Torres and Antonio Mart{\'i}n-Duce and Fernando Jos{\'e} Corrales and Huiying Yang and Jes{\'u}s Prieto and Shelly C Lu and Juan Caballer{\'i}a and J. J. Rodes and Jose M. Mato},
  journal={Journal of hepatology},
  year={2000},
  volume={33 6},
  pages={
          907-14
        }
}
BACKGROUND/AIMS It has been known for at least 50 years that alterations in methionine metabolism occur in human liver cirrhosis. However, the molecular basis of this alteration is not completely understood. In order to gain more insight into the mechanisms behind this condition, mRNA levels of methionine adenosyltransferase (MAT1A), glycine methyltransferase (GNMT), methionine synthase (MS), betaine homocysteine methyltransferase (BHMT) and cystathionine beta-synthase (CBS) were examined in 26… CONTINUE READING
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