Reduced longevity in untreated patients with isolated growth hormone deficiency.

@article{Besson2003ReducedLI,
  title={Reduced longevity in untreated patients with isolated growth hormone deficiency.},
  author={Am{\'e}lie Besson and Souzan Salemi and Sabina Gallati and Arthur Jenal and Rudolf Horn and Pia S Mullis and Primus E. Mullis},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2003},
  volume={88 8},
  pages={3664-7}
}
Increased longevity of hypopituitary dwarf mice and GH- resistant knockout mice appears to be in contrast with observations made in clinical practice. In humans, on one hand hypopituitarism and GH deficiency (GHD) are believed to constitute risk factors for cardiovascular disease and, therefore, early death. But on the other hand, patients with a PROP-1… CONTINUE READING