Reduced-intensity transplantation for lymphomas using haploidentical related donors vs HLA-matched unrelated donors.

@article{Kanate2016ReducedintensityTF,
  title={Reduced-intensity transplantation for lymphomas using haploidentical related donors vs HLA-matched unrelated donors.},
  author={Abraham Sebastian Kanate and Alberto Mussetti and Mohamed A Kharfan-Dabaja and Kwang Woo Ahn and Alyssa DiGilio and Amer M Beitinjaneh and Saurabh Chhabra and Timothy S. Fenske and Cesar Freytes and Robert Peter Gale and Siddhartha S. Ganguly and M. D. Vicki Stover Hertzberg and Evgeny Klyuchnikov and Hillard M Lazarus and Richard F. Olsson and M L Perales and Andrew R. Rezvani and Marcie L. Riches and Ayman Saad and Shimon Slavin and Sonali M Smith and Anna Sureda and Jean A Yared and Stefan O Ciurea and Philippe F Armand and Rachel B. Salit and Javier Bola{\~n}os-Meade and Mehdi Hamadani},
  journal={Blood},
  year={2016},
  volume={127 7},
  pages={938-47}
}
We evaluated 917 adult lymphoma patients who received haploidentical (n = 185) or HLA-matched unrelated donor (URD) transplantation either with (n = 241) or without antithymocyte globulin (ATG; n = 491) following reduced-intensity conditioning regimens. Haploidentical recipients received posttransplant cyclophosphamide-based graft-versus-host disease (GVHD) prophylaxis, whereas URD recipients received calcineurin inhibitor-based prophylaxis. Median follow-up of survivors was 3 years. The 100… CONTINUE READING
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