Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele.

@article{Cao2016ReducedHV,
  title={Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele.},
  author={Bo Cao and Isabelle E. Bauer and Ajaykumar N. Sharma and Benson Mwangi and Thomas W. Frazier and Luca Lavagnino and Giovana B. Zunta-Soares and Consuelo Walss-Bass and David C. Glahn and Fl{\'a}vio Pereira Kapczinski and David A. Nielsen and Jair C. Soares},
  journal={Journal of affective disorders},
  year={2016},
  volume={198},
  pages={
          198-205
        }
}
BACKGROUND Previous studies investigated the impact of brain-derived neurotrophic factor (BDNF) val66met (rs6265) on hippocampus volumes and neurocognition in bipolar disorders (BD), but the results were not consistent. This study aimed to investigate the effect of BDNF polymorphism on hippocampus volumes and memory performance in well-characterized adult populations diagnosed with type I BD (BD-I) and major depressive disorder (MDD) compared with healthy controls (HC). METHODS 48 BD-I… CONTINUE READING

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derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder. Journal of affective disorders

  • A. Cunha, B. N. Frey, +5 authors F. Kapczinski
  • Neuroscience letters
  • 2006
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