Reduced gray matter volume in the anterior cingulate, orbitofrontal cortex and thalamus as a function of mild depressive symptoms: a voxel-based morphometric analysis.

@article{Webb2014ReducedGM,
  title={Reduced gray matter volume in the anterior cingulate, orbitofrontal cortex and thalamus as a function of mild depressive symptoms: a voxel-based morphometric analysis.},
  author={Christian A. Webb and Mareen Weber and Elizabeth A Mundy and William D. S. Killgore},
  journal={Psychological medicine},
  year={2014},
  volume={44 13},
  pages={2833-43}
}
BACKGROUND Studies investigating structural brain abnormalities in depression have typically employed a categorical rather than dimensional approach to depression [i.e., comparing subjects with Diagnostic and Statistical Manual of Mental Disorders (DSM)-defined major depressive disorder (MDD) v. healthy controls]. The National Institute of Mental Health, through their Research Domain Criteria initiative, has encouraged a dimensional approach to the study of psychopathology as opposed to an over… CONTINUE READING
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