Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly.

@article{Convit2003ReducedGT,
  title={Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly.},
  author={Antonio Convit and Oliver T. Wolf and Chaim Y Tarshish and Mony J de Leon},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2003},
  volume={100 4},
  pages={2019-22}
}
Poor glucose tolerance and memory deficits, short of dementia, often accompanies aging. The purpose of this study was to ascertain whether, among nondiabetic, nondemented middle-aged and elderly individuals, poorer glucose tolerance is associated with reductions in memory performance and smaller hippocampal volumes. We studied 30 subjects who were evaluated consecutively in an outpatient research setting. The composition of the participant group was 57% female and 68.6 +/- 7.5 years of age; the… CONTINUE READING
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