Reduced functional connectivity within and between ‘social’ resting state networks in autism spectrum conditions

  title={Reduced functional connectivity within and between ‘social’ resting state networks in autism spectrum conditions},
  author={Elisabeth A. H. von dem Hagen and Raliza S. Stoyanova and Simon Baron-Cohen and Andrew J. Calder},
  booktitle={Social cognitive and affective neuroscience},
Individuals with autism spectrum conditions (ASC) have difficulties in social interaction and communication, which is reflected in hypoactivation of brain regions engaged in social processing, such as medial prefrontal cortex (mPFC), amygdala and insula. Resting state studies in ASC have identified reduced connectivity of the default mode network (DMN), which includes mPFC, suggesting that other resting state networks incorporating 'social' brain regions may also be abnormal. Using seed-based… CONTINUE READING
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