Reduced food intake in response to CGP 71683A may be due to mechanisms other than NPY Y5 receptor blockade

@article{Zuana2001ReducedFI,
  title={Reduced food intake in response to CGP 71683A may be due to mechanisms other than NPY Y5 receptor blockade},
  author={O. D. Zuana and M. Sadlo and M. Germain and M. F{\'e}l{\'e}tou and S. Chamorro and F. Tisserand and C. D. Montrion and JF Boivin and J. Duhault and J. Boutin and N. Levens},
  journal={International Journal of Obesity},
  year={2001},
  volume={25},
  pages={84-94}
}
INTRODUCTION: The purpose of this study was to test the continuing validity of the hypothesis that neuropeptide Y (NPY) produced in the brain controls food intake through an interaction with the NPY Y5 receptor subtype.METHODS: The hypothesis was tested using CGP 71683A a potent and highly selective non-peptide antagonist of the NPY Y5 receptor which was administered into the right lateral ventricle of obese Zucker fa/fa rats.RESULTS: Intraventricular injection of 3.4 nmol/kg NPY increased food… Expand
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  • B. Beck
  • Biology, Medicine
  • Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2006
TLDR
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TLDR
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