Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas.

Abstract

Microsatellite instability (MIN) is frequently observed in hereditary nonpolyposis colon cancer and in other sporadic cancers including gliomas. Abnormalities in at least one of five mismatch repair (MMR) genes are implicated in the development of cancers in hereditary nonpolyposis colon cancer and the associated MIN. Using a newly developed multiplex… (More)

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@article{Wei1997ReducedEO, title={Reduced expression of mismatch repair genes measured by multiplex reverse transcription-polymerase chain reaction in human gliomas.}, author={Qing Wei and Melissa L Bondy and L Mao and Y Gaun and L Cheng and Joan E. R. Cunningham and Y Fan and Janet M. Bruner and W. K. Alfred Yung and V. A. Levin and Athanassios P. Kyritsis}, journal={Cancer research}, year={1997}, volume={57 9}, pages={1673-7} }