Reduced expression of claudin-7 is associated with poor outcome in non-small cell lung cancer.

Abstract

Claudin-7 is a tight junction protein that plays an important role in tumorigenesis, tumor invasion and metastasis. We examined the clinical significance of claudin-7 expression in 75 postsurgical non-small cell lung cancer (NSCLC) patients. Claudin-7 expression was measured immunohistochemically and was found to be high in 25 patients (33.3%) and low in 50… (More)

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@article{Yamamoto2010ReducedEO, title={Reduced expression of claudin-7 is associated with poor outcome in non-small cell lung cancer.}, author={Taketsugu Yamamoto and Takashi Oshima and Kazue Yoshihara and Sumitaka Yamanaka and Teppei Nishii and Hiromasa Arai and Kenji Inui and Takeshi Kaneko and Akinori Nozawa and Tetsukan Woo and Yasushi Rino and Munetaka Masuda and Toshio Imada}, journal={Oncology letters}, year={2010}, volume={1 3}, pages={501-505} }