Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease

  title={Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease},
  author={Petr Ricanek and Lisa Kristina Lunde and Stephan A. Frye and Mari St\oen and St{\aa}le Nyg{\aa}rd and Jens Preben Morth and Andreas Rydning and Morten Harald Vatn and Mahmood Amiry-Moghaddam and Tone T\onjum},
  booktitle={Clinical and experimental gastroenterology},
OBJECTIVES The aim of this study was to investigate the relationship between aquaporin (AQP) water channel expression and the pathological features of early untreated inflammatory bowel disease (IBD) in humans. METHODS Patients suspected to have IBD on the basis of predefined symptoms, including abdominal pain, diarrhea, and/or blood in stool for more than 10 days, were examined at the local hospital. Colonoscopy with biopsies was performed and blood samples were taken. Patients who did not… CONTINUE READING
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Annual review of medicine • 2012
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