Reduced expression of angiotensin I-converting enzyme in caveolin-1 knockout mouse lungs.

@article{Maniatis2010ReducedEO,
  title={Reduced expression of angiotensin I-converting enzyme in caveolin-1 knockout mouse lungs.},
  author={Nikolaos A. Maniatis and Irina V. Balyasnikova and R. Metzger and Maricela Castellon and David J. Visintine and David E. Schwartz and Richard D Minshall and Sergei M Danilov},
  journal={Microvascular research},
  year={2010},
  volume={80 2},
  pages={250-7}
}
Reduced lung capillary expression of angiotensin I-converting enzyme (ACE), a key enzyme in cardiovascular pathophysiology, and of caveolin-1, an important regulator of endothelial cell signalling, has been demonstrated in various models of pulmonary arterial hypertension (PAH). We addressed the relationship between PAH and ACE expression in caveolin-1… CONTINUE READING