Reduced expression of COXs and production of prostaglandin E(2) in patients with nasal polyps with or without aspirin-intolerant asthma.

Abstract

BACKGROUND Researchers have debated whether regulation of the COX enzymes (COX-1 and COX-2), which mediate production of prostaglandins (PGs), affects the pathogenesis of nasal polyps (NPs) and aspirin-intolerant asthma (AIA). OBJECTIVE We investigated the roles of PGE(2), COX-1 and COX-2, and PGE(2) receptors in the development of NPs and AIA by… (More)
DOI: 10.1016/j.jaci.2011.01.065

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Cite this paper

@article{RocaFerrer2011ReducedEO, title={Reduced expression of COXs and production of prostaglandin E(2) in patients with nasal polyps with or without aspirin-intolerant asthma.}, author={Jordi Roca-Ferrer and Francesc Josep Garcia-Garcia and Javier Pereda and Mar{\'i}a del Carmen P{\'e}rez-Gonz{\'a}lez and Laura Pujols and Isam Alobid and Joaquim Mullol and C{\'e}sar Picado}, journal={The Journal of allergy and clinical immunology}, year={2011}, volume={128 1}, pages={66-72.e1} }