Reduced excitability of the motor cortex in untreated patients with de novo idiopathic "grand mal" seizures.

@article{Delvaux2001ReducedEO,
  title={Reduced excitability of the motor cortex in untreated patients with de novo idiopathic "grand mal" seizures.},
  author={Val{\'e}rie Delvaux and Giovanna Alagona and Pascale G{\'e}rard and Victor de Pasqua and P. J. Delwaide and Alain Maertens de Noordhout},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2001},
  volume={71 6},
  pages={772-6}
}
OBJECTIVES Transcranial magnetic stimulation (TMS) was used to investigate motor cortex excitability, intracortical excitatory, and inhibitory pathways in 18 patients having experienced a first "grand mal" seizure within 48 hours of the electrophysiological test. All had normal brain MRI, and were free of any treatment, drug, or alcohol misuse. Results were compared with those of 35 age matched normal volunteers. METHODS The following parameters of responses to TMS were measured: motor… CONTINUE READING

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