Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.
@article{Damsgaard2009ReducedEV, title={Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men.}, author={C. Damsgaard and L. Lauritzen and P. Calder and T. R. Kjaer and H. Fr{\o}kiaer}, journal={The Journal of nutrition}, year={2009}, volume={139 7}, pages={ 1410-4 } }
Fish oil (FO) is considered antiinflammatory, but evidence regarding its effect on human cytokine production is conflicting. High linoleic acid (LA) intake may impair any effects of FO. The aim of this study was to investigate how FO combined with high or low LA intake affected ex vivo cytokine production from cultures of whole blood, peripheral blood mononuclear cells (PBMC), and monocytes in healthy men. The study was a double-blinded, controlled, 2 x 2 factorial 8-wk intervention. Sixty-four… CONTINUE READING
Topics from this paper
Paper Mentions
Interventional Clinical Trial
The purpose of this study is to investigate the effects of long-chain n-3 polyunsaturated
fatty acids (n-3 LCPUFA) on immune function and cardiovascular disease risk
Conditions | Cardiovascular Heart Disease, Metabolic Syndrome |
---|---|
Intervention | Behavioral |
21 Citations
Reduced ex vivo stimulated IL-6 response in infants randomized to fish oil from 9 to 18 months, especially among PPARG2 and COX2 wild types.
- Biology, Medicine
- Prostaglandins, leukotrienes, and essential fatty acids
- 2015
- 8
The impact of fish-oil fatty acids on postprandial vascular reactivity (959.22)
- Medicine
- 2014
- Highly Influenced
- PDF
Effects of similar intakes of marine n-3 fatty acids from enriched food products and fish oil on cardiovascular risk markers in healthy human subjects
- Medicine, Biology
- British Journal of Nutrition
- 2011
- 22
- PDF
Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice.
- Medicine, Biology
- The Journal of nutrition
- 2012
- 56
- PDF
DHA derivatives of fish oil as dietary supplements: a nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicity
- Biology, Medicine
- Expert opinion on drug discovery
- 2012
- 11
Effects of Olive Oil on Markers of Inflammation and Endothelial Function—A Systematic Review and Meta-Analysis
- Medicine
- Nutrients
- 2015
- 103
- Highly Influenced
- PDF
Effects of omega-3 polyunsaturated fatty acid supplementation in patients with chronic chagasic cardiomyopathy: study protocol for a randomized controlled trial
- Medicine
- Trials
- 2013
- 13
- Highly Influenced
- PDF
The pro-/anti-inflammatory effects of different fatty acids on visceral adipocytes are partially mediated by GPR120
- Chemistry, Medicine
- European Journal of Nutrition
- 2016
- 24
Dietary fatty acids modulate adipocyte TNFa production via regulation of its DNA promoter methylation levels.
- Biology, Medicine
- The Journal of nutritional biochemistry
- 2017
- 12
The differential effects of EPA and DHA on cardiovascular risk factors.
- Chemistry, Medicine
- The Proceedings of the Nutrition Society
- 2011
- 189
- PDF
References
SHOWING 1-10 OF 30 REFERENCES
Low dose supplementation with two different marine oils does not reduce pro-inflammatory eicosanoids and cytokines in vivo.
- Biology, Medicine
- Asia Pacific journal of clinical nutrition
- 2006
- 20
- PDF
Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell composition and function in healthy humans.
- Biology, Medicine
- The American journal of clinical nutrition
- 2004
- 247
- PDF
The effects of fish oil and high or low linoleic acid intake on fatty acid composition of human peripheral blood mononuclear cells
- Medicine, Biology
- British Journal of Nutrition
- 2007
- 26
- PDF
Cytokine secretion and eicosanoid production in the peripheral blood mononuclear cells of MS patients undergoing dietary supplementation with n-3 polyunsaturated fatty acids
- Biology, Medicine
- Journal of Neuroimmunology
- 1995
- 241
Activation state alters the effect of dietary fatty acids on pro-inflammatory mediator production by murine macrophages.
- Biology, Medicine
- Cytokine
- 2000
- 71
Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men.
- Biology, Medicine
- The American journal of clinical nutrition
- 2006
- 339
- PDF
Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects.
- Biology, Medicine
- The British journal of nutrition
- 2003
- 203
- PDF
Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function.
- Biology, Medicine
- The American journal of clinical nutrition
- 2003
- 181
- PDF
The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects.
- Biology, Medicine
- The British journal of nutrition
- 2004
- 120
- PDF
Dietary fish oil decreases C-reactive protein, interleukin-6, and triacylglycerol to HDL-cholesterol ratio in postmenopausal women on HRT.
- Biology, Medicine
- The Journal of nutritional biochemistry
- 2003
- 133