Reduced efficacy of treatment of strongyloidiasis in HTLV-I carriers related to enhanced expression of IFN-gamma and TGF-beta1.

@article{Satoh2002ReducedEO,
  title={Reduced efficacy of treatment of strongyloidiasis in HTLV-I carriers related to enhanced expression of IFN-gamma and TGF-beta1.},
  author={Masao Satoh and Hiromu Toma and Yoshihiro Sato and Masahiro Takara and Yoshiyuki Shiroma and Susumu Kiyuna and Kenji Hirayama},
  journal={Clinical and experimental immunology},
  year={2002},
  volume={127 2},
  pages={
          354-9
        }
}
Strongyloidiasis, a human intestinal infection caused by Strongyloides stercoralis (S. stercoralis), is difficult to cure with drugs. In particular, a decrease of the efficacy of treatment has been reported in patients dually infected with S. stercoralis and human T-cell leukaemia virus type I (HTLV-I), both of which are endemic in Okinawa, Japan. However, the factors influencing this resistance remain unclear. In the present study, patients infected with S. stercoralis, with or without HTLV-I… CONTINUE READING

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