Reduced anterior cingulate and orbitofrontal volumes in child abuse-related complex PTSD.

@article{Thomaes2010ReducedAC,
  title={Reduced anterior cingulate and orbitofrontal volumes in child abuse-related complex PTSD.},
  author={Kathleen Thomaes and Ethy Dorrepaal and Nel P. J. Draijer and Michiel B. de Ruiter and Anton Jlm van Balkom and Johannes H Smit and Dick J. Veltman},
  journal={The Journal of clinical psychiatry},
  year={2010},
  volume={71 12},
  pages={
          1636-44
        }
}
OBJECTIVE Classic posttraumatic stress disorder (PTSD) is associated with smaller hippocampus, amygdala, and anterior cingulate cortex (ACC) volumes. We investigated whether child abuse-related complex PTSD--a severe form of PTSD with affect dysregulation and high comorbidity--showed similar brain volume reductions. METHOD We used voxel-based morphometry to measure gray matter concentrations in referred outpatients with child abuse-related complex PTSD (n = 31) compared to matched healthy… CONTINUE READING

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