Reduced ampicillin bioavailability following oral coadministration with chloroquine.

@article{Ali1985ReducedAB,
  title={Reduced ampicillin bioavailability following oral coadministration with chloroquine.},
  author={Hafiz M Muazzam Ali},
  journal={The Journal of antimicrobial chemotherapy},
  year={1985},
  volume={15 6},
  pages={781-4}
}
Ampicillin bioavailability was examined in seven healthy adult male volunteers after oral coadministration with chloroquine using the urinary excretion method. Ampicillin (500 mg, capsules) and chloroquine phosphate (250 mg, tablets) were administered in single doses of 1.0 g each. Each subject received, on two different occasions, ampicillin alone and ampicillin together chloroquine. Urine was collected hourly for 8.0 h. Ampicillin urinary levels were measured chemically. The mean % dose… CONTINUE READING