• Medicine
  • Published in Neuroscience letters 1985

Reduced activity of locus coeruleus neurons in hypertensive rats.

@article{Olpe1985ReducedAO,
  title={Reduced activity of locus coeruleus neurons in hypertensive rats.},
  author={Hans Rudolf Olpe and Kathleen H. Berecek and Roland S. G. Jones and Martin W. Steinmann and Christel Sonnenburg and Karl G. Hofbauer},
  journal={Neuroscience letters},
  year={1985},
  volume={61 1-2},
  pages={
          25-9
        }
}
The influence of blood pressure on locus coeruleus (LC) neuronal activity was investigated in chloral hydrate anesthetized rats. Mean spontaneous firing rate of LC neurons was reduced by 25% in deoxycorticosterone acetate (DOCA-salt) treated Sprague-Dawley rats and by 19% in spontaneously hypertensive rats (SHR) as compared to their corresponding control animals. In acute experiments performed on normotensive rats, peripherally induced blood pressure changes elicited reciprocal changes in cell… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Altered central catecholaminergic transmission and cardiovascular disease.

VIEW 1 EXCERPT
CITES RESULTS

Role of the locus ceruleus in baroreceptor regulation of supraoptic vasopressin neurons in the rat.

VIEW 3 EXCERPTS
CITES BACKGROUND