Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet.

@article{Rada2010ReducedAD,
  title={Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet.},
  author={Pedro V Rada and Miriam E. Bocarsly and Jessica R Barson and Bartley G. Hoebel and Sarah F. Leibowitz},
  journal={Physiology & behavior},
  year={2010},
  volume={101 3},
  pages={394-400}
}
Obese humans and animals exhibit reduced functioning of the dopamine (DA) system in the nucleus accumbens (NAc). The question addressed here is whether this change in NAc DA can be detected in Sprague-Dawley rats that are prone to obesity on a fat-rich diet but still at normal body weight. Rats were subgrouped as "obesity-prone" (OP) or "obesity-resistant" (OR), based on their weight gain during 5days of access to a high-fat diet, and were then shifted to a lower-fat chow diet before… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 61 references

Leptin resistance: a prediposing factor for diet-induced obesity.

American journal of physiology. Regulatory, integrative and comparative physiology • 2009

Orosensory perception of dietary lipids in mammals.

Results and problems in cell differentiation • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…