Reduced Susceptibility to Colitis-Associated Colon Carcinogenesis in Mice Lacking Plasma Membrane-Associated Sialidase

@inproceedings{Yamaguchi2012ReducedST,
  title={Reduced Susceptibility to Colitis-Associated Colon Carcinogenesis in Mice Lacking Plasma Membrane-Associated Sialidase},
  author={Kazunori Yamaguchi and Kazuhiro Shiozaki and Setsuko Moriya and Koichi Koseki and Tadashi Wada and Hiroo Tateno and Ikuro Sato and Masahide Asano and Yoichiro Iwakura and Taeko Miyagi},
  booktitle={PloS one},
  year={2012}
}
Sialic acids are acidic monosaccharides that bind to the sugar chains of glycoconjugates and change their conformation, intermolecular interactions, and/or half-life. Thus, sialidases are believed to modulate the function of sialoglycoconjugates by desialylation. We previously reported that the membrane-associated mammalian sialidase NEU3, which… CONTINUE READING