Reduced Risk of Prostate Cancer With 5α-Reductase Inhibitors.
@article{Thompson2018ReducedRO, title={Reduced Risk of Prostate Cancer With 5α-Reductase Inhibitors.}, author={I. Thompson and P. Goodman and C. Tangen}, journal={Journal of the National Cancer Institute}, year={2018}, volume={110 11}, pages={ 1159-1160 } }
Prostate cancer (PCA) and lower urinary tract symptoms (LUTS) associated with aging and benign prostatic hyperplasia are ubiquitous in aging men. PCA has a high prevalence, causes considerable morbidity when metastatic, and is the third most common cause of cancer death in men (1). LUTS adversely affects quality of life and may result in recurrent infections and urinary retention, leading to morbidity and mortality among older men. A seminal clinical trial compared the efficacy of two… CONTINUE READING
Topics from this paper
One Citation
References
SHOWING 1-10 OF 12 REFERENCES
Risk of Prostate Cancer in Men Treated With 5&agr;-Reductase Inhibitors—A Large Population-Based Prospective Study
- Medicine
- Journal of the National Cancer Institute
- 2018
- 12
- PDF
The influence of finasteride on the development of prostate cancer.
- Medicine
- The New England journal of medicine
- 2003
- 2,462
- PDF
The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia.
- Medicine
- The New England journal of medicine
- 2003
- 1,608
- PDF
Effect of finasteride on the sensitivity of PSA for detecting prostate cancer.
- Medicine
- Journal of the National Cancer Institute
- 2006
- 275
- PDF
Active surveillance for prostate cancer: current evidence and contemporary state of practice
- Medicine
- Nature Reviews Urology
- 2016
- 145
Pathologic Characteristics of Cancers Detected in the Prostate Cancer Prevention Trial: Implications for Prostate Cancer Detection and Chemoprevention
- Medicine
- Cancer Prevention Research
- 2008
- 101
- PDF
Finasteride Does Not Increase the Risk of High-Grade Prostate Cancer: A Bias-Adjusted Modeling Approach
- Medicine
- Cancer Prevention Research
- 2008
- 186
- PDF
Biases in Recommendations for and Acceptance of Prostate Biopsy Significantly Affect Assessment of Prostate Cancer Risk Factors: Results From Two Large Randomized Clinical Trials.
- Medicine
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- 2016
- 25
Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0 ng/ml or lower.
- Medicine
- JAMA
- 2005
- 635
- PDF
Finasteride improves the sensitivity of digital rectal examination for prostate cancer detection.
- Medicine
- The Journal of urology
- 2007
- 93