Reduced RNA synthesis levels in isolated mouse liver nuclei following reaction with [(H2O)(NH3)5Ru(II)]2+

Abstract

The goal of this study is to establish the effect of [(H2O)(NH3)5Ru(II)]2+ reaction of nuclei on their RNA transcription levels. This question is important because ammineruthenium compounds share chemical and biological properties with the chemotherapeutic agent cis-dichlorodiammineplatinum(II) or cisplatin. First we demonstrate that mouse liver nuclei are… (More)
DOI: 10.1007/BF00225219

Topics

7 Figures and Tables

Cite this paper

@article{Marx1989ReducedRS, title={Reduced RNA synthesis levels in isolated mouse liver nuclei following reaction with [(H2O)(NH3)5Ru(II)]2+}, author={Kenneth A. Marx and Christopher Seery and Patrick C. Malloy}, journal={Molecular and Cellular Biochemistry}, year={1989}, volume={90}, pages={37-45} }