Reduced Physiological Complexity in Robust Elderly Adults with the APOE ε4 Allele

@inproceedings{Cheng2009ReducedPC,
  title={Reduced Physiological Complexity in Robust Elderly Adults with the APOE ε4 Allele},
  author={Daniel I. Cheng and Shih-Jen Tsai and C N Hong and Albert C. Yang},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND It is unclear whether the loss of physiological complexity during the aging process is due to genetic variations. The APOE gene has been studied extensively in regard to its relationship with aging-associated medical illness. We hypothesize that diminished physiological complexity, as measured by heart rate variability, is influenced by polymorphisms in the APOE allele among elderly individuals. METHODOLOGY/PRINCIPAL FINDINGS A total of 102 robust, non-demented, elderly subjects… CONTINUE READING