Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle‐age period

Abstract

Although it is known that the regenerative function of neural stem/progenitor cells (NSPCs) declines with age, causal mechanisms underlying this phenomenon are not understood. Here, we systematically analyze subventricular zone (SVZ) NSPCs, in various groups of rats across the aging spectrum, using in vitro and in vivo histological and behavioral techniques… (More)
DOI: 10.1111/acel.12482

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