Reduced Incidence of Nodal Micrometastasis after Major Response to Neoadjuvant Chemoradiation in Locally Advanced Esophageal Cancer

@article{Prenzel2006ReducedIO,
  title={Reduced Incidence of Nodal Micrometastasis after Major Response to Neoadjuvant Chemoradiation in Locally Advanced Esophageal Cancer},
  author={Klaus Ludwig Prenzel and Alexandra Koenig and Paul Magnus Schneider and Christian Schnickmann and Stephan Ernst Baldus and Wolfgang Schroeder and E. Bollschweiler and Hans Peter Dienes and Rolf Peter M{\"u}ller and Jakob Robert Izbicki and Arnulf H Hoelscher},
  journal={Annals of Surgical Oncology},
  year={2006},
  volume={14},
  pages={954-959}
}
Neoadjuvant treatment modalities for esophageal cancer were developed to improve local tumor control as well as to reduce lymph node metastases and distant metastases in patients with locally advanced esophageal cancer. The influence on nodal micrometastasis has not yet been evaluated. This study includes 52 patients with localized (cT2-4, Nx, M0) esophageal cancers (21 adenocarcinomas, 31 squamous cell cancers) who received neoadjuvant chemoradiation (36Gy, 5-FU, cisplatin) followed by… CONTINUE READING

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