Reduced IL-10 secretion by CD4+ T lymphocytes expressing mutant cystic fibrosis transmembrane conductance regulator (CFTR).

@article{Moss1996ReducedIS,
  title={Reduced IL-10 secretion by CD4+ T lymphocytes expressing mutant cystic fibrosis transmembrane conductance regulator (CFTR).},
  author={Richard B. Moss and Robert C. Bocian and Y P Hsu and Yao Jun Dong and Mariska Kemna and Tao Wei and Phyllis Gardner},
  journal={Clinical and experimental immunology},
  year={1996},
  volume={106 2},
  pages={374-88}
}
Expression of the CFTR protein is thought to be physiologically important only in exocrine epithelial cells. However, chronic respiratory inflammation and infection remain unexplained phenomena in disease pathogenesis. Non-transformed, antigen-responsive CD4+ T cells cloned from healthy controls and CF patients homozygous or heterozygous for the delta F508… CONTINUE READING