Reduced Expression of the Polymeric Immunoglobulin Receptor in Pancreatic and Periampullary Adenocarcinoma Signifies Tumour Progression and Poor Prognosis

Abstract

The polymeric immunoglobulin receptor (pIgR) is a key component of the mucosal immune system that mediates epithelial transcytosis of immunoglobulins. High pIgR expression has been reported to correlate with a less aggressive tumour phenotype and an improved prognosis in several human cancer types. Here, we examined the expression and prognostic… (More)
DOI: 10.1371/journal.pone.0112728

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Cite this paper

@inproceedings{Fristedt2014ReducedEO, title={Reduced Expression of the Polymeric Immunoglobulin Receptor in Pancreatic and Periampullary Adenocarcinoma Signifies Tumour Progression and Poor Prognosis}, author={Richard Fristedt and Jacob Elebro and Alexander Gaber and Liv Jonsson and Margareta Heby and Yulyana Yudina and Bj{\"{o}rn Nodin and Mathias Uhl{\'e}n and Jakob Eberhard and Karin Jirstr{\"{o}m}, booktitle={PloS one}, year={2014} }