Reduced E-cadherin expression is associated with lymph node metastases in laryngeal squamous cell carcinoma.

@article{Li2012ReducedEE,
  title={Reduced E-cadherin expression is associated with lymph node metastases in laryngeal squamous cell carcinoma.},
  author={Jing-jia Li and Gehua Zhang and Xin-ming Yang and Shi-sheng Li and Xian Liu and Qin-tai Yang and Yuan Li and Jin Ye},
  journal={Auris, nasus, larynx},
  year={2012},
  volume={39 2},
  pages={186-92}
}
OBJECTIVE To investigate the expression of E-cadherin and its relationship with clinicopathological parameters in laryngeal squamous cell carcinoma (LSCC). METHODS Sixty-four patients who had previously undergone complete resection of tumor for LSCC were studied retrospectively. The level of E-cadherin expression in tumor tissues and paired nontumor tissues were determined by immunohistochemistry. RESULTS The expression of E-cadherin in tumor tissues was significantly lower than nontumor… CONTINUE READING
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