Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development.

@article{Finnegan1996ReducedDM,
  title={Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development.},
  author={E Jean Finnegan and W James Peacock and Elizabeth S Dennis},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 16},
  pages={8449-54}
}
Arabidopsis plants transformed with an antisense construct of an Arabidopsis methyltransferase cDNA (METI) have reduced cytosine methylation in CG dinucleotides. Methylation levels in progeny of five independent transformants ranged from 10% to 100% of the wild type. Removal of the antisense construct by segregation in sexual crosses did not fully restore methylation patterns in the progeny, indicating that methylation patterns are subject to meiotic inheritance in Arabidopsis. Plants with… CONTINUE READING
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