Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder

@article{Hediger2008ReducedBC,
  title={Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder},
  author={Mary L. Hediger and Lucinda J England and Cynthia A. Molloy and Kai-fun Yu and Patricia Manning-Courtney and James L. Mills},
  journal={Journal of Autism and Developmental Disorders},
  year={2008},
  volume={38},
  pages={848-856}
}
Bone development, casein-free diet use, supplements, and medications were assessed for 75 boys with autism or autism spectrum disorder, ages 4–8 years. Second metacarpal bone cortical thickness (BCT), measured on hand-wrist radiographs, and % deviations in BCT from reference medians were derived. BCT increased with age, but % deviations evidenced a progressive fall-off (p = .02): +3.1 ± 4.7%, −6.5 ± 4.0%, −16.6 ± 3.4%, −19.4 ± 3.7%, −24.1 ± 4.4%, at ages 4–8, respectively, adjusting for height… Expand
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