Reduced Axin Protein Expression Is Associated with a Poor Prognosis in Patients with Squamous Cell Carcinoma of Esophagus

@article{Li2009ReducedAP,
  title={Reduced Axin Protein Expression Is Associated with a Poor Prognosis in Patients with Squamous Cell Carcinoma of Esophagus},
  author={PhD Anna Fen-Yau Li and Po-Kuei Hsu and Ching Tzao and Ying-Jan Wang and BS I-ChunHung and M N Huang and PhD Han-Shui Hsu},
  journal={Annals of Surgical Oncology},
  year={2009},
  volume={16},
  pages={2486-2493}
}
Our study investigates the significance of the expression of Wnt pathway proteins including β-catenin, Axin, β-transducin-repeat-containing protein (β-TrCP), and adenomatous polyposis coli (APC) in squamous cell carcinoma of the esophagus (ESCC). Immunohistochemical analysis was performed on paraffin-embedded tissue specimens from 128 resected ESCC tumors to detect the expression of β-catenin, Axin, β-TrCP, and APC. Correlation between immunoexpression, clinicopathological parameters, and… CONTINUE READING

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