Reduced-Antigen, Combined Diphtheria, Tetanus, and Acellular Pertussis Vaccine, Adsorbed (Boostrix®)

@article{Scott2012ReducedAntigenCD,
  title={Reduced-Antigen, Combined Diphtheria, Tetanus, and Acellular Pertussis Vaccine, Adsorbed (Boostrix{\textregistered})},
  author={Lesley J. Scott and Paul L. McCormack},
  journal={BioDrugs},
  year={2012},
  volume={27},
  pages={75-81}
}
Reduced-antigen, combined diphtheria, tetanus, and three-component acellular pertussis vaccine (Tdap; Boostrix®) is indicated for booster vaccination against diphtheria, tetanus, and pertussis. In clinical trials, a single booster dose of Tdap induced high seroprotective levels of antibodies to its three component acellular pertussis antigens in virtually all children and adolescents, and in a high proportion of adults and elderly individuals, at ≈1 month post-vaccination, irrespective of their… 
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Clinical results complement the technical data and support the use of the new syringe presentation to deliver the dTpa vaccine.

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Immune persistence after pertussis vaccination

Data on immune persistence after different pertussis vaccinations is presented and the findings from countries with different vaccination strategies are compared.

Pertussis re-emergence in the post-vaccination era

The simultaneous use of more than one strategy, including cocooning strategy plus vaccination of adolescents and adults, seems to be the most reasonable preventive measure for the control of pertussis.

Predictors of Full Childhood Immunization Status in Owerri, Nigeria

This study investigated the influence of maternal satisfaction with postnatal services and paternal support on full childhood immunization status and examined the association between maternal factors and the maternal retention of immunization documentation in Owerri, Nigeria to help to evolve a system that may increase childhood immunized status and reduce vaccine-preventable diseases in Owarri and serve as a model for other countries.

The promise of reverse vaccinology.

Machine learning methods have been used to improve the ability of RV approaches to identify vaccine candidates and it is envisaged that RV approaches will facilitate rapid vaccine design with less reliance on conventional animal testing and clinical trials in order to curb the threat of antibiotic resistance or newly emerged outbreaks of bacterial origin.

Calendario de vacunaciones de la Asociación Española de Pediatría: Recomendaciones 2022

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Clinical Experimental Vaccine Research

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