Corpus ID: 35420891

Reduced Adipose Tissue Oxygenation in Human Obesity-Evidence for Rarefaction , Macrophage Chemotaxis and Inflammation without an Angiogenic Response

@inproceedings{Pasarica2008ReducedAT,
  title={Reduced Adipose Tissue Oxygenation in Human Obesity-Evidence for Rarefaction , Macrophage Chemotaxis and Inflammation without an Angiogenic Response},
  author={Magdalena Pasarica and Olga R. Sereda and Leanne Maree Redman and Diana C. Albarado and David T. Hymel and Laura E. Roan and Jennifer Rood and David Burk and Steven R. Smith and Pennington},
  year={2008}
}
  • Magdalena Pasarica, Olga R. Sereda, +7 authors Pennington
  • Published 2008
  • Objective: Based on rodent studies, we examined the hypothesis that increased adipose tissue mass in obesity without an adequate support of vascularization might lead to hypoxia, macrophage infiltration and inflammation. Research Design and Methods: Oxygen partial pressure [AT pO2] and temperature [AT temperature] in abdominal adipose tissue [9 lean, 12 overweight/obese men and women] was measured by direct insertion of a polarographic Clark electrode. Body composition was measured by DEXA… CONTINUE READING

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