Redox tunable delivery systems: sweet block copolymer micelles via thiol-(bromo)maleimide conjugation.

Abstract

Oligosaccharide-based block copolymers (OBCPs) are synthesized by thiol click conjugation using reducing-end thiol-containing xyloglucooligosaccharides and maleimide- or bromomaleimide-terminated polycaprolactone. The self-assembled OBCPs in aqueous solution lead to redox-sensitive micelles with different responsiveness. This distinguishing feature allows us to control the release of entrapped hydrophobic Nile red by mixing both OBCPs.

Cite this paper

@article{Petrelli2016RedoxTD, title={Redox tunable delivery systems: sweet block copolymer micelles via thiol-(bromo)maleimide conjugation.}, author={Antoine Petrelli and Redouane Borsali and S{\'e}bastien Fort and Sami Halila}, journal={Chemical communications}, year={2016}, volume={52 82}, pages={12202-12205} }