Redox signalling in anchorage-dependent cell growth.

  title={Redox signalling in anchorage-dependent cell growth.},
  author={Paola Chiarugi and Tania Fiaschi},
  journal={Cellular signalling},
  volume={19 4},
Current data have provided new perspectives concerning the regulation of non-transformed cell proliferation in response to both soluble growth factors and to adhesive cues. Non-transformed cells are anchorage dependent for the execution of the mitotic program and cannot avoid the concomitant signals starting from mitogenic molecules, as growth factors, and adhesive agents belonging to extracellular matrix. Reactive oxygen species play a key role during both growth factor and integrin receptor… CONTINUE READING
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